November 27, 2009
The Smithsonian Tropical Research Institute invites applications for a postdoctoral position in Natural Products Chemistry (NPC) to work at the University of Panama as part of the International Cooperative Biodiversity Groups located in Panama. The main task of the position is to develop research activity focused on 1) development of cultures of microorganisms, 2) isolation and characterization of bioactive compounds present in cultures of microorganisms and 3) use of bioanalytical assays to guide the isolation of active compounds.
The successful candidate will conduct research in the purification, scale-up and structural determination of bioactive compounds and crude fractions isolated from extracts prepared from microorganisms. A primary responsibility of the incumbent will be to develop natural product extraction, purification and stabilization methods for bioactives and crude fractions deemed important by our project. The candidate will be familiar with the use of modern analytical methods including the use of GC-MS, NMR, IR, and UV. Responsibilities include maintenance and upkeep of our 300 MHz Bruker NMR
The successful candidate will be responsible for:
- Preparation of various extracts or fractions of materials from extracts prepared from microorganism and assistance in their purification and characterization;
- Optimization of extraction and purification processes in the laboratory;
- Development of fractionation/purification methods by using various chromatography tools such as preparative HPLC and open column chromatography;
- Working and communicating effectively in an interdisciplinary research environment
- Communication of experimental results with other members of the group,
- Performance of general duties related to day-to-day laboratory operations, such as ordering supplies, waste tracking and disposal, etc;
- Other duties as delegated by the supervisor.
Candidates should have a PhD in Natural Products Chemistry and a minimum of two years practical experience in an academic or applied research environment. The successful applicant will have practical work experience in a modern analytical chemistry laboratory. He/She will have knowledge of natural products chemistry and of modern analytical chemistry practices and theory. The candidate must have demonstrated, hands-on experience in isolation, purification, and structural characterization of natural products. The candidate must have hands-on experience with analytical method development using HPLC and low pressure chromatography methods. The candidate has to demonstrated ability to rum NMR experiments. In addition, the applicant must be detail oriented and able to work independently, be computer literate and proficient in Microsoft Word, Excel and statistical analysis programs, possess strong spoken and written communication skills, and have good interpersonal skills. An enhanced reliability security check is required.
From January to December, 2010 with possibility of extension (subject to funding and performance)
Please submit: CV, including contact information of 3 references (address, phone, and email) and list of your experimental expertise
Contact: Luis Cubilla-Rios, PhD.
Email address: email@example.com