PhD Student – Immunopathology of Malaria during pregnancy

4 01 2010

Centre de Recerca en Salut Intermacional de Barcelona

PhD Student – Immunopathology of Malaria during pregnancy

The Barcelona Centre for International Health Research (CRESIB) is a global health research institute developed from some of the leading academic and biomedical research institutions in Barcelona, together with the Catalan Government, as a response to emerging international health challenges.

CRESIB was founded in July 2006 by the Generalitat de Catalunya, the Universitat de Barcelona (UB), Hospital Clínic de Barcelona (HCB) and the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). The centre is located in a privileged scientific environment, alongside the HCB, IDIBAPS and the Campus of the Facultat de Medicina-Clínic August Pi i Sunyer of the UB.

CRESIB promotes a multidisciplinary approach and excellence in research, and also collaborates with other research centres from developed and less-developed countries.

CRESIB is seeking an enthusiastic, organized and autonomous PhD student who is interested in applying for a grant to work on the Immunopathology of Malaria during pregnancy.

Reports to:
Alfredo Mayor

To develop a PhD in the context of a project entitled “Role of immune-endocrine factors during pregnancy on the susceptibility to malaria and mother-infant health at delivery”. This project has recently been funded by the Instituto de Salud Carlos III (Ministerio de Ciencia e Innovación, Spain). In order to improve malaria treatment during pregnancy and design new prophylactic strategies, this project aims to study the role of maternal immune-endocrine factors in the susceptibility of pregnant women to Plasmodium falciparum. To achieve this, we aim to determine humoral and cellular immunity (malaria specific and general) and levels of hormones in different time-points during pregnancy of 530 Mozambican women exposed to malaria, and to evaluate their association with indicators of maternal/infant health at delivery.

Main duties/ responsibilities:

Apply for grants to obtain PhD funding.

Develop immunological and parasitological techniques in CRESIB’s laboratory.

Travel to Mozambique to supervise the recruitment of pregnant women and laboratory work in the Centro en Investigaçao em Saúde da Manhiça, and to contribute to capacity building of Mozambican researchers.

Analyse and prepare manuscripts presenting results obtained during the research.

Develop a thesis on the main topic of the project.

Minimum requirements
Graduate level degree in biology/biochemist/pharmacy

Self-motivation, eagerness to grow professionally and commitment to self-development.
IT skills (PC-Windows preferred).

Fluency in written and spoken Spanish, Catalan. Reading and writing in English.


Applicants must send a CV and a cover letter to:

Alfredo Mayor





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